Genotype/phenotype relations: mouse and human infant models of attention and memory

Abstract

Studies of human and animal genomes/epigenomes are becoming increasingly detailed, yet phenotyping remains surprisingly limited.  It is critical that infant and adult human tasks at the neural and cognitive levels, and not merely at the behavioural levels, are aligned with those used to test genotype/phenotype correlations in animals. The doctoral candidate would be trained in infant/adult phenotyping, and in the development of new experimental tasks to be piloted on mouse models, human infants and adults.  These would initially be standardized on typical participants and, once successful, would be extended to mouse/human models of neurodevelopmental syndromes such as Down syndrome.





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Biological Areas:

Neurobiology
Genetics

BBSRC Area:

Genes, development and STEM approaches to biology