In order to survive, animals need to accurately detect danger. In humans and other animals, social visual signals can be used to communicate information about threat to other individuals. Threat detecting systems are likely to involve dedicated neural mechanisms, and recruit ancient (subcortical) circuits for arousal and attention. The aims of this project are to investigate whether and how these ancient circuits may represent the presence and position of unseen threats. To achieve this the project will combine behavioural and physiological measures in humans, using eye tracking and pupillometry, with counterpart behavioural and direct electrophysiological measurements in mouse.
Sears RM, Fink AE, Wigestrand MB, Farb CR, de Lecea L, Ledoux JE.(2013) Proc Natl Acad Sci 110(50): 20260-20265
Ewbank MP, Jennings C, Calder AJ (2009) Journal of Vision 9(12):16.1-7
Rigoli F, Ewbank M, Dalgleish T, Calder A. (2016) Neurosci Letters, 26;612:7-13
Jun YY, Mareschal I, Clifford CW, Dadds MR. Psychiatry Res. (2013),210(1):193-8