This project will encompass cell biology, molecular biology, and biophysics, including spectroscopy and molecular microscopy to investigate the functional consequences of temporal cycling due to the circadian clock in cyanobacterium Synechococcus elongatus PCC 7942. This will involve interdisciplinary studies for designing and characterizing "clock protein" knock-out mutants, then using state-of-the-art physical methods (including measurements at high end international research facilities) to characterize these cyanobacteria, altering ambient conditions to establish the effect that the surrounding medium has on the circadian clock. Additionally the project will trace the extent of linkage between the clock and the functions of secretion and motility.
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