An integrative approach to evaluate physiological health by characterizing microbiome and host interaction using saliva samples.


The microbiome is involved in human metabolism, nutrition, physiology, and immune function therefore associated with both health and disease1. Among human microbiome populations, saliva’s microbiome provides a powerful non-invasive option for developing biomarkers describing health and disease. Our aim is to use novel statistical integrative approaches while combining host (mRNA) and microbiome (mRNA and DNA) saliva-derived profiles to identify novel non-invasive biomarkers. In this project we will functionally characterize the salivary microbiome in healthy individuals based on age and diet; secondly, we will challenge the ability of saliva’s microbiome to describe health by comparing to individuals with chronic intestinal disease.


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Biological Areas:



Plants, microbes, food and sustainability