Grid cells are neurons in the Entorhinal cortex of the rat whose firing is tuned to the position of the animal with multiple firing fields , laid out across the environment in a regular hexagonal lattice. Theoretical models have proposed a 2-dimensional continuous attractor as the network architecture underlying grid cell firing. However, how such a network could be wired up during development remains unknown. This project will use a combination of electrophysiological recording and neural network modeling to discover what are the network mechanisms underlying grid cell development.
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