Synthetic biology aims to engineer organisms to perform useful medical or industrial functions. To control these functions, gene circuits will be required that can operate reliably in environments that are noisy, changing over time and subject to sometimes poorly defined interactions with the host cell. Therefore designing dependable gene circuits that can function safely over a wide range of conditions is paramount to the successful development of all synthetic biological applications. For example this might include the safe, controlled delivery of novel therapeutics in the human gut or release of toxins to destroy disease vectors only when they become hosts.
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